Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394195 | 0.80 | TSHR (0.48) | ALDH1A1CYP1A2GAAMGAMSI | |
| SCHEMBL2352990 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TRPA1CYP1A2GAAMGAM | |
| SCHEMBL1863674 | 0.74 | CYP1A2 (0.47) | ALDH1A1TRPA1CYP1A2GAAMGAM | |
| SCHEMBL28078421 | 0.72 | CYP1A2 (0.45) | ALDH1A1TRPA1CYP1A2GAAMGAM | |
| SCHEMBL4702420 | 0.72 | CYP1A2 (0.45) | ALDH1A1TRPA1CYP1A2GAAMGAM | |
| Succinic Acid Diethyl Ester SCHEMBL27768067 | 0.71 | GAA (0.67) | ALDH1A1TRPA1CYP1A2GAAMGAM | |
| Succinic Acid Diethyl Ester SCHEMBL22780 | 0.71 | GAA (0.67) | ALDH1A1TRPA1CYP1A2GAAMGAM | |
| SCHEMBL23484497 | 0.71 | CYP1A2 (0.44) | ALDH1A1TRPA1CYP1A2GAAMGAM | |
| SCHEMBL5109822 | 0.71 | CYP1A2 (0.44) | ALDH1A1TRPA1CYP1A2GAAMGAM | |
| SCHEMBL14032871 | 0.70 | CYP1A2 (0.40) | ALDH1A1TRPA1CYP1A2GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101828552-B | Methods of blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE | 2014-09-24 | — | — | CN | disclosed |
| US-20110190137-A1 | METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | JACOBSON RICHARD MARTIN | 2011-08-04 | — | — | US | disclosed |
| CN-1450859-B | Method for blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE | 2011-08-03 | — | — | CN | disclosed |
| CN-101828552-A | Method with the cyclopropene derivatives blocking ethylene response in plants | UNIV NORTH CAROLINA STATE | 2010-09-15 | — | — | CN | disclosed |
| EP-1409440-A4 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM & HAAS (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | JACOBSON RICHARD MARTIN (US) | 2005-03-24 | — | — | US | disclosed |
| EP-1409440-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| EP-1233669-B1 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2004-02-25 | — | — | EP | disclosed |
| CN-1450859-A | method for blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE (US) | 2003-10-22 | — | — | CN | disclosed |
| WO-2002068367-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| EP-1233669-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6365549-B2 | PRESERVATION | NORTH CAROLINA STATE UNIVERSITY | 2002-04-02 | — | — | US | disclosed |
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | NORTH CAROLINA STATE UNIVERSITY | 2001-09-06 | — | — | US | disclosed |
| WO-2001037663-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | PRUNE1, NOTUM, FAR1 | ALDH1A1 3933/4885TRPA1 3584/4885CYP1A2 3293/4885 |
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | ERN1, CTH, CBS | ALDH1A1 4370/4885TRPA1 3331/4885CYP1A2 1503/4885 |
| US-20110190137-A1 | METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ERN1, CTH, CBR3 | ALDH1A1 4363/4885TRPA1 3497/4885CYP1A2 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.