Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301092 | 0.87 | L3MBTL1 (0.45) | L3MBTL1TRPV1KCNH2CES2PNMT | |
| SCHEMBL23522701 | 0.83 | L3MBTL1 (0.44) | L3MBTL1TRPV1KCNH2TACR1KMT2A | |
| SCHEMBL19283805 | 0.82 | L3MBTL1 (0.45) | L3MBTL1TRPV1KCNH2CES2PNMT | |
| SCHEMBL19301144 | 0.80 | FAAH (0.41) | L3MBTL1TRPV1KCNH2KMT2AMEN1 | |
| SCHEMBL26830389 | 0.76 | CES2 (0.50) | L3MBTL1CES2SOS1PNMTKMT2A | |
| SCHEMBL11336248 | 0.76 | ACP3 (0.50) | L3MBTL1CES2SOS1PNMTKMT2A | |
| SCHEMBL6702950 | 0.76 | MAPT (0.46) | CES2SOS1PNMTKMT2AAURKA | |
| SCHEMBL6700680 | 0.76 | PNMT (0.53) | L3MBTL1CES2PNMTKMT2AMEN1 | |
| SCHEMBL22630847 | 0.75 | AURKA (0.59) | CES2SOS1PNMTAURKA | |
| SCHEMBL12895165 | 0.75 | AURKA (0.59) | CES2SOS1PNMTAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017144183-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2017-08-31 | — | — | WO | disclosed |