SCHEMBL2680340

SCHEMBL2680340

CCCCCCCCCCCCCCCC[Si](C)C

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
THRB P10828 1/20 0.53
DNM1 Q05193 7/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC22A1 O15245 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17090832 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL502963 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL502669 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090753 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2679212 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL476071 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL475858 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090826 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9658795 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL235247 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103370043-B Retention type non-solid oil connectivity skin conditioning composition containing 12-hydroxy stearic acid 荷兰联合利华有限公司 2016-08-10 CN claimed
CN-118702765-B Method for purifying polypeptide 天津博蕴纯化装备材料科技有限公司 2024-12-24 CN disclosed
WO-2024225003-A1 COMPOSITION FOR PEST CONTROL AND PHOTOSTABILITY METHOD FOR PEST CONTROL COMPONENT 大日本除蟲菊株式会社 2024-10-31 WO disclosed
CN-106146851-B Photocurable composition and cured product containing same 信越化学工业株式会社 2020-10-23 CN disclosed
US-10730904-B2 Method for liquid-phase synthesis of nucleic acid TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-08-04 US disclosed
EP-2921499-B1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACIDS TAKEDA PHARMACEUTICALS CO (JP) 2020-01-22 EP disclosed
EP-3093303-B1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2019-08-28 EP disclosed
US-20190135852-A1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-05-09 US disclosed
US-20160333171-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-11-17 US disclosed
EP-3093303-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT Shin-Etsu Chemical Co., Ltd. (JP) 2016-11-16 EP disclosed
EP-2921499-A1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID Takeda Pharmaceutical Company Limited (JP) 2015-09-23 EP disclosed
CN-104736204-A Method for improving the appearance of aging in skin by modulating WIPI-1 AVON PROD INC 2015-06-24 CN disclosed
US-8921836-B2 Polymer compound, and thin film and ink composition each containing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-30 US disclosed
US-8436166-B2 Amino-containing vinylsilane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-07 US disclosed
US-20120305899-A1 POLYMER COMPOUND, AND THIN FILM AND INK COMPOSITION EACH CONTAINING SAME NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY (JP) 2012-12-06 US disclosed
US-20120116037-A1 ORGANIC THIN FILM TRANSISTOR, SURFACE LIGHT SOURCE AND DISPLAY DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-10 US disclosed
US-20100317852-A1 AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-16 US disclosed
US-20100249319-A1 POLYMER COMPOUND, METHOD FOR PRODUCING THE SAME, AND COMPOSITION CONTAINING THE POLYMER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-30 US disclosed
EP-2208745-A1 POLYMER COMPOUND, METHOD FOR PRODUCING THE SAME, AND COMPOSITION CONTAINING THE POLYMER COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-07-21 EP disclosed
EP-0517262-A1 Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190135852-A1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID RNGTT, POLR2H, POLR2E TSHR 551/4885THRB 1506/4885DNM1 2698/4885
US-20100317852-A1 AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD BHMT2, GNMT, VASP TSHR 4723/4885THRB 4098/4885DNM1 1617/4885
US-10730904-B2 Method for liquid-phase synthesis of nucleic acid RNGTT, POLR2H, POLR2E TSHR 411/4885THRB 1249/4885DNM1 1968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.