SCHEMBL23525619

SCHEMBL23525619

CC(C)(C)c1ccc(-c2ccccn2)cc1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 1/20 0.41
▸ KDM4E B2RXH2 5/20 0.41
▸ LMNA P02545 3/20 0.41
▸ POLB P06746 2/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ CCR1 P32246 1/20 0.41
▸ CCR5 P51681 1/20 0.41
▸ CCR8 P51685 1/20 0.41
▸ METAP1 P53582 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ DOHH Q9BU89 1/20 0.41
▸ P4HTM Q9NXG6 1/20 0.41
▸ MAPT P10636 4/20 0.40
▸ RAB9A P51151 3/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ NPSR1 Q6W5P4 3/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ PDK2 Q15119 1/20 0.40
▸ HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26424745 0.82 KDM4E (0.45) TRPV1KDM4ELMNAPOLBCYP1A2
SCHEMBL26426730 0.81 KDM4E (0.47) TRPV1KDM4ELMNAPOLBCYP1A2
SCHEMBL28129414 0.79 KDM4E (0.50) KDM4ELMNAPOLBCYP1A2CCR1
SCHEMBL30610285 0.78 NPC1 (0.47) KDM4ELMNAPOLBCYP1A2CCR1
SCHEMBL23525622 0.78 NPC1 (0.47) KDM4ELMNAPOLBCYP1A2CCR1
SCHEMBL11124529 0.77 ALDH1A1 (0.46) TRPV1KDM4ELMNAPOLBCYP1A2
SCHEMBL2754785 0.77 PIK3CD (0.46) TRPV1KDM4ELMNAPOLBCYP1A2
SCHEMBL29175406 0.75 CRHBP (0.45) KDM4ELMNAMAPTALDH1A1HSD17B10
SCHEMBL70728 0.75 PIK3CD (0.49) KDM4ELMNAPOLBCYP1A2CCR1
SCHEMBL28129410 0.75 KDM4E (0.50) KDM4ELMNAPOLBCYP1A2CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12120945-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-10-15 — — US disclosed
US-20230247897-A1 Phosphorescent Excimers with Preferred Molecular Orientation as Monochromatic Emitters for Display And Lighting Applications UNITED STATES DEPARTMENT OF ENERGY 2023-08-03 — — US disclosed
US-20230247897-A1 Phosphorescent Excimers with Preferred Molecular Orientation as Monochromatic Emitters for Display And Lighting Applications UNITED STATES DEPARTMENT OF ENERGY 2023-08-03 — — US disclosed
US-11594688-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-02-28 — — US disclosed
US-20210193936-A1 PHOSPHORESCENT EXCIMERS WITH PREFERRED MOLECULAR ORIENTATION AS MONOCHROMATIC EMITTERS FOR DISPLAY AND LIGHTING APPLICATIONS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-06-24 — — US disclosed
CN-111527615-A Phosphorescent excimer molecules with preferred molecular orientation as monochromatic emitters for display and lighting applications 李健 2020-08-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210193936-A1 PHOSPHORESCENT EXCIMERS WITH PREFERRED MOLECULAR ORIENTATION AS MONOCHROMATIC EMITTERS FOR DISPLAY AND LIGHTING APPLICATIONS PDCD1LG2, DCX, EMC2 TRPV1 1589/4885KDM4E 4324/4885LMNA 4079/4885
US-11594688-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters PDCD1LG2, EML4, EMC3 TRPV1 1457/4885KDM4E 4181/4885LMNA 4085/4885
US-12120945-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters PDCD1LG2, EML4, EMC3 TRPV1 1457/4885KDM4E 4181/4885LMNA 4085/4885
US-20230247897-A1 Phosphorescent Excimers with Preferred Molecular Orientation as Monochromatic Emitters for Display And Lighting Applications PDCD1LG2, DCX, EMC2 TRPV1 1589/4885KDM4E 4324/4885LMNA 4079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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