Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237397 | 0.86 | MEN1 (0.35) | ARSMN1; SMN2 | |
| SCHEMBL3383990 | 0.83 | LMNA (0.38) | CTSSCTSLCTSKCYP2D6CYP2C19 | |
| SCHEMBL21482392 | 0.81 | LMNA (0.33) | CTSSCTSLCTSKCYP2D6SMN1; SMN2 | |
| SCHEMBL6548070 | 0.81 | HDAC3 (0.32) | CTSSCTSLCTSKSMN1; SMN2NPC1 | |
| SCHEMBL4659778 | 0.78 | ESR2 (0.32) | — | |
| SCHEMBL15669159 | 0.78 | CTSS (0.32) | CTSSCTSLCTSKNPC1RAB9A | |
| SCHEMBL235262 | 0.78 | CES2 (0.33) | CTSLARGAA | |
| SCHEMBL237868 | 0.77 | ALDH1A1 (0.36) | CTSSCTSLCTSKSMN1; SMN2NPC1 | |
| SCHEMBL466361 | 0.77 | NR4A2 (0.37) | CTSSCTSLCTSKCYP3A4CYP2C19 | |
| SCHEMBL14865070 | 0.77 | HDAC3 (0.35) | CTSSCTSLCTSKCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |