Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059477 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL5654410 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL5654406 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL13683800 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL5143351 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL18045690 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL20892596 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL702232 | 0.84 | ALDH1A1 (0.71) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL14195830 | 0.84 | MAOB (0.62) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL4063273 | 0.84 | MAOB (0.62) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026218-B2 | Bifunctional analgesic compounds for opioid receptor agonists and neurokinin-1 receptor antagonists | THE UNIVERSITY OF ARIZONA (US) | 2011-09-27 | — | — | US | claimed |
| US-20080039404-A1 | BIFUNCTIONAL ANALGESIC COMPOUNDS FOR OPIOID RECEPTOR AGONISTS AND NEUROKININ-1 RECEPTOR ANTAGONISTS | UNIVERSITY OF ARIZONA (US) | 2008-02-14 | — | — | US | claimed |
| US-20050130228-A1 | Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form | H. LUNDBECK A/S (DK) | 2005-06-16 | — | — | US | claimed |
| US-20030138847-A1 | Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form | H. LUNDBECK A/S (DK) | 2003-07-24 | — | — | US | claimed |
| EP-1268050-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. Lundbeck A/S (DK) | 2003-01-02 | — | — | EP | claimed |
| WO-2001068598-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. LUNDBECK A/S (DK) | 2001-09-20 | — | — | WO | claimed |
| US-11952434-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-09 | — | — | US | disclosed |
| US-20230101323-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-03-30 | — | — | US | disclosed |
| CN-114652813-A | Macrocyclic peptides as immunomodulators | 百时美施贵宝公司 | 2022-06-24 | — | — | CN | disclosed |
| US-11358988-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-06-14 | — | — | US | disclosed |
| CN-107108698-B | Macrocyclic peptides as immunomodulators | 百时美施贵宝公司 | 2022-04-29 | — | — | CN | disclosed |
| US-20220017572-A1 | GEMINOID LIPOPEPTIDE COMPOUNDS AND THEIR USES | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2022-01-20 | — | — | US | disclosed |
| EP-3778622-A1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20020058654-A1 | Substituted aminoalkylamide derivatives as antagonists of follicle stimulating hormone | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-05-16 | — | — | US | disclosed |
| US-20020037859-A1 | 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases | AVENTISUB INC. | 2002-03-28 | — | — | US | disclosed |
| WO-2001068598-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. LUNDBECK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001016113-A1 | TRACELESS SOLID PHASE SYNTHESIS OF AROMATIC AND HETEROAROMATIC COMPOUNDS | SIDDCO (US) | 2001-03-08 | — | — | WO | disclosed |
| EP-1078002-A1 | PEPTIDE ANTIANGIOGENIC DRUGS | ABBOTT LABORATORIES (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999061476-A1 | PEPTIDE ANTIANGIOGENIC DRUGS | ABBOTT LABORATORIES (US) | 1999-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952434-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | ALDH1A1 1217/4885MAOB 3066/4885L3MBTL1 1391/4885 |
| US-20020058654-A1 | Substituted aminoalkylamide derivatives as antagonists of follicle stimulating hormone | FSHR, GNRHR, SHBG | ALDH1A1 2217/4885MAOB 152/4885L3MBTL1 4619/4885 |
| US-20230101323-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | ALDH1A1 1217/4885MAOB 3066/4885L3MBTL1 1391/4885 |
| US-20220017572-A1 | GEMINOID LIPOPEPTIDE COMPOUNDS AND THEIR USES | NGLY1, NR2C2, NR2E1 | ALDH1A1 4840/4885MAOB 4667/4885L3MBTL1 2048/4885 |
| US-11358988-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | ALDH1A1 1217/4885MAOB 3066/4885L3MBTL1 1391/4885 |
| US-20020037859-A1 | 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases | MMP3, MMP1, MMP9 | ALDH1A1 281/4885MAOB 198/4885L3MBTL1 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.