Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23527318 | 0.85 | L3MBTL1 (0.50) | RARBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23527275 | 0.83 | KMT2A (0.47) | RARBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2560579 | 0.80 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL14028290 | 0.74 | HPGD (0.46) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL416455 | 0.73 | HSD11B1 (0.51) | RARBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23527289 | 0.72 | KMT2A (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5637948 | 0.72 | RAB9A (0.47) | RARBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14424589 | 0.71 | HTR2A (0.49) | RARBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18540517 | 0.70 | GRK6 (0.52) | MAPTALDH1A1KDM4E | |
| SCHEMBL23527341 | 0.70 | KMT2A (0.45) | MAPTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600704-B2 | Substituted 1,2,4-triazoles and methods of use | STINGINN LLC (US) | 2026-04-14 | — | — | US | disclosed |
| EP-4075980-B1 | SUBSTITUTED 1,2, 4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| US-20250163005-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2025-05-22 | — | — | US | disclosed |
| US-12134605-B2 | Substituted 1,2,4-triazoles and methods of use | STINGINN, LLC (US) | 2024-11-05 | — | — | US | disclosed |
| US-20240262796-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2024-08-08 | — | — | US | disclosed |
| US-20210188786-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2021-06-24 | — | — | US | disclosed |
| US-20210188786-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2021-06-24 | — | — | US | disclosed |
| WO-2021127282-A1 | SUBSTITUTED 1,2, 4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188786-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STING1, IRF3, CGAS | RARB 1772/4885MAPT 4824/4885ALDH1A1 3318/4885 |
| US-12134605-B2 | Substituted 1,2,4-triazoles and methods of use | STING1, IRF3, CGAS | RARB 1772/4885MAPT 4824/4885ALDH1A1 3318/4885 |
| US-12600704-B2 | Substituted 1,2,4-triazoles and methods of use | STING1, IRF3, MAVS | RARB 2030/4885MAPT 4720/4885ALDH1A1 3818/4885 |
| US-20250163005-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STING1, IRF3, CGAS | RARB 1772/4885MAPT 4824/4885ALDH1A1 3318/4885 |
| US-20240262796-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STING1, IRF3, CGAS | RARB 1772/4885MAPT 4824/4885ALDH1A1 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.