SCHEMBL2352773

SCHEMBL2352773

Cc1nc(C(F)(F)F)ccc1C(=O)C1=C(O)C2CCC(C2)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
PDE2A O00408 2/20 0.34
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32
TUBB2B Q9BVA1 1/20 0.32
TUBB1 Q9H4B7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2352779 1.00 LMNA (0.40) LMNAGAANPC1RAB9APDE2A
SCHEMBL6375278 0.89 LMNA (0.40) LMNAGAANPC1RAB9APDE2A
SCHEMBL6375283 0.89 LMNA (0.40) LMNAGAANPC1RAB9APDE2A
SCHEMBL6379425 0.88 LMNA (0.39) LMNAGAANPC1RAB9A
SCHEMBL6379421 0.88 LMNA (0.39) LMNAGAANPC1RAB9A
SCHEMBL3272484 0.84 TUBB4A (0.31) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3272492 0.84 TUBB4A (0.31) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL6379445 0.81 GAA (0.37) LMNAGAANPC1RAB9A
SCHEMBL6379439 0.81 GAA (0.37) LMNAGAANPC1RAB9A
SCHEMBL6374093 0.81 RBP4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2258177-A2 Mixtures comprising 1-methylcyclopropene Rohm and Haas Company (US) 2010-12-08 EP claimed
EP-2164323-A1 MIXTURES COMPRISING 1-METHYLCYCLOPROPENE Rohm and Haas Company (US) 2010-03-24 EP claimed
EP-1937069-B1 HERBICIDAL COMPOSITIONS BASED ON 3-PHENYLURACILS AND N-[[4-[(CYCLOPROPYLAMINO)-CARBONYL]PHENYL]SULFONYL]-2-METHOXYBENZAMIDE BASF SE (DE) 2009-09-30 EP claimed
US-20080300139-A1 Method for Controlling Aquatic Weeds BASF SE (DE) 2008-12-04 US claimed
US-20080254985-A1 Herbicidal Compositions Based on 3-Phenyluracils and N-[[4-[Cyclopropylamino)-Carbonyl]Phenyl]Sulfonyl]-2-Methoxybenzamide BASF SE (DE) 2008-10-16 US claimed
EP-1965648-A2 A METHOD FOR CONTROLLING AQUATIC WEEDS BASF SE (DE) 2008-09-10 EP claimed
EP-1605758-B1 HERBICIDAL MIXTURES BASED ON 3-PHENYLURACILS BASF SE (DE) 2008-09-10 EP claimed
EP-1937069-A2 HERBICIDAL COMPOSITIONS BASED ON 3-PHENYLURACILS AND N-[[4-[(CYCLOPROPYLAMINO)-CARBONYL]PHENYL]SULFONYL]-2-METHOXYBENZAMIDE BASF SE (DE) 2008-07-02 EP claimed
WO-2008071714-A1 MIXTURES COMPRISING 1-METHYLCYCLOPROPENE ROHM AND HAAS COMPANY (US) 2008-06-19 WO claimed
WO-2007071761-A2 A METHOD FOR CONTROLLING AQUATIC WEEDS BASF SE (DE) 2007-06-28 WO claimed
WO-2007042447-A2 HERBICIDAL COMPOSITIONS BASED ON 3-PHENYLURACILS AND N-[[4-[(CYCLOPROPYLAMINO)-CARBONYL]PHENYL]SULFONYL]-2-METHOXYBENZAMIDE BASF SE (DE) 2007-04-19 WO claimed
US-20060293187-A1 Herbicidal mixtures based on 3-phenyluracils BASF AKTIENGESELLSCHAFT (DE) 2006-12-28 US claimed
EP-2863743-B1 ADJUVANT COMPRISING A 2-PROPYLHEPTYLAMINE ALKOXYLATE, SUGAR-BASED SURFACTANT, AND DRIFT-CONTROL AGENT AND HUMECTANT BASF SE (DE) 2018-04-11 EP disclosed
US-9814233-B2 Composition comprising a pesticide, a surfactant and an alkoxylate of 2-propyheptylamine BASF SE (DE) 2017-11-14 US disclosed
EP-2680692-B1 COMPOSITION COMPRISING A PESTICIDE, AN ALKOXYLATE OF 2-PROPYLHEPTYLAMINE AND A FURTHER SURFACTANT BASF SE (DE) 2017-04-12 EP disclosed
US-9210930-B2 Control of submerged aquatic vegetation BASF SE (DE) 2015-12-15 US disclosed
US-20020016345-A1 Pyridine ketones useful as herbicides SYNGENTA PARTICIPATIONS AG (CH) 2002-02-07 US disclosed
WO-2001054501-A2 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2001-08-02 WO disclosed
EP-1114030-A1 PYRIDINE KETONES USEFUL AS HERBICIDES Syngenta Participations AG (CH) 2001-07-11 EP disclosed
WO-2000015615-A1 PYRIDINE KETONES USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2000-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060293187-A1 Herbicidal mixtures based on 3-phenyluracils CBR3, CYP2W1, DDT LMNA 3690/4885GAA 4237/4885NPC1 4394/4885
US-20020016345-A1 Pyridine ketones useful as herbicides DDT, PDHA1, IDH2 LMNA 4284/4885GAA 721/4885NPC1 4388/4885
US-20080254985-A1 Herbicidal Compositions Based on 3-Phenyluracils and N-[[4-[Cyclopropylamino)-Carbonyl]Phenyl]Sulfonyl]-2-Methoxybenzamide DDT, ABCC5, CBR3 LMNA 3837/4885GAA 1271/4885NPC1 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.