Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BCL9 | O00512 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809029 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL28063215 | 0.86 | CES1 (0.42) | ALDH1A1CES2CES1TSHRLMNA | |
| SCHEMBL29093389 | 0.83 | TSHR (0.57) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL28063153 | 0.83 | DGKA (0.53) | ALDH1A1CES2CES1TSHRLMNA | |
| SCHEMBL28063152 | 0.83 | DGKA (0.53) | ALDH1A1CES2CES1TSHRLMNA | |
| SCHEMBL1289306 | 0.80 | ALDH1A1 (0.36) | ALDH1A1FFAR3TSHR | |
| SCHEMBL7058927 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL23529421 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL27365865 | 0.77 | DGKA (0.47) | ALDH1A1DGKA | |
| SCHEMBL12504352 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CES2CES1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378362-B2 | Polydiorganosiloxane preparation | DOW SILICONES CORPORATION (US) | 2025-08-05 | — | — | US | disclosed |
| US-20230013216-A1 | POLYDIORGANOSILOXANE PREPARATION | DOW SILICONES CORPORATION | 2023-01-19 | — | — | US | disclosed |
| EP-4077482-A1 | POLYDIORGANOSILOXANE PREPARATION | Dow Silicones Corporation (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021119972-A1 | POLYDIORGANOSILOXANE PREPARATION | DOW SILICONES CORPORATION (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-103391947-B | Stabilization of polymers containing hydrolyzable functional groups | 株式会社普利司通 | 2016-08-24 | — | — | CN | disclosed |