Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12504305 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CES2CES1FFAR3HDAC3 | |
| SCHEMBL12504214 | 0.80 | DGKA (0.38) | ALDH1A1CES2CES1LMNATSHR | |
| SCHEMBL7758098 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CES2CES1LMNAFFAR3 | |
| SCHEMBL23529414 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CES2CES1LMNAFFAR3 | |
| SCHEMBL7759950 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CES2CES1LMNAFFAR3 | |
| SCHEMBL7058927 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CES2CES1LMNAFFAR3 | |
| SCHEMBL4394880 | 0.73 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL3809029 | 0.72 | ALDH1A1 (0.57) | ALDH1A1CES2CES1LMNAFFAR3 | |
| SCHEMBL21378198 | 0.72 | — | — | |
| SCHEMBL524128 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658877-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | Bridgestone Corporation (JP) | 2013-11-06 | — | — | EP | disclosed |
| WO-2012092626-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |