SCHEMBL1289306

SCHEMBL1289306

CCC(=O)O[SiH](OC)OC

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 3/20 0.33
NAAA Q02083 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
FFAR3 O14843 1/20 0.32
MGAM O43451 2/20 0.31
GAA P10253 2/20 0.31
SI P14410 2/20 0.31
MGAM2 Q2M2H8 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SOAT1 P35610 1/20 0.31
CYP1A2 P05177 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
BLM P54132 1/20 0.30
WRN Q14191 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7893861 0.95 ALDH1A1 (0.36) ALDH1A1TSHRNAAATDP1FFAR3
SCHEMBL338659 0.86 ALDH1A1 (0.41) ALDH1A1TSHRNAAATDP1FFAR3
SCHEMBL23529414 0.80 ALDH1A1 (0.50) ALDH1A1TSHRFFAR3
SCHEMBL838935 0.77 ALDH1A1 (0.35) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL7055151 0.77
SCHEMBL28063215 0.77 CES1 (0.42) ALDH1A1TSHR
SCHEMBL28995208 0.75 MGAM (0.56) ALDH1A1TSHRMGAMGAASI
SCHEMBL28063153 0.73 DGKA (0.53) ALDH1A1TSHRTDP1HSD17B10
SCHEMBL25333172 0.73 ALOX15 (0.33) ALDH1A1NAAACYP2C19
SCHEMBL1498107 0.72 ALDH1A1 (0.39) ALDH1A1TSHRNAAATDP1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378362-B2 Polydiorganosiloxane preparation DOW SILICONES CORPORATION (US) 2025-08-05 US claimed
CN-114901725-B Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-09-08 CN claimed
US-20230013216-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION 2023-01-19 US claimed
EP-4077482-A1 POLYDIORGANOSILOXANE PREPARATION Dow Silicones Corporation (US) 2022-10-26 EP claimed
CN-114901725-A Preparation of polydiorganosiloxane 美国陶氏有机硅公司 2022-08-12 CN claimed
WO-2021119972-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION (US) 2021-06-24 WO claimed
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same DOW SILICONES CORPORATION (US) 2026-05-12 US disclosed
EP-4086705-B1 TONER CANON KK (JP) 2026-03-25 EP disclosed
EP-4012501-B1 EXTERNAL ADDITIVE FOR TONER, TONER AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-02-11 EP disclosed
EP-3654105-B1 PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-01-28 EP disclosed
EP-4519346-B1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2026-01-14 EP disclosed
US-12497509-B2 Method for manufacturing a silicone elastomer article using a 3D printer ELKEM SILICONES FRANCE SAS (FR) 2025-12-16 US disclosed
US-12487539-B2 Fine particle, external additive for toners, and toner CANON KABUSHIKI KAISHA (JP) 2025-12-02 US disclosed
WO-2013013111-A1 YTTRIUM CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-01-24 WO disclosed
WO-2013009836-A1 SAMARIUM CONTAINING COMPLEXES AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-01-17 WO disclosed
WO-2013009840-A1 LANTHANIDE COMPLEXES WITH IMIDAZOLE LIGANDS FOR CONDENSATION REACTIONS DOW CORNING CORPORATION (US) 2013-01-17 WO disclosed
WO-2012134788-A1 COMPOSITIONS CONTAINING PHOSPHATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012134784-A1 COMPOSITIONS CONTAINING PHOSPHONATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012134786-A1 COMPOSITIONS CONTINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012047312-A1 BIODEGRADABLE HYDROPHOBIC CELLULOSIC SUBSTRATES AND METHODS FOR THEIR PRODUCTION USING REACTIVE SILANES DOW CORNING CORPORATION (US) 2012-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same HAO2, H1-2, HRH2 ALDH1A1 596/4885TSHR 549/4885NAAA 3520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.