Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23530747 | 0.89 | ALOX5 (0.31) | KLKB1HPGD | |
| SCHEMBL23530871 | 0.89 | RAB9A (0.39) | KLKB1METTL3KDM4EPOLB | |
| SCHEMBL23531003 | 0.84 | KLKB1 (0.40) | KLKB1METTL3KDM4EALDH1A1POLB | |
| SCHEMBL23530583 | 0.83 | KLKB1 (0.43) | KLKB1METTL3 | |
| SCHEMBL23530882 | 0.83 | KLKB1 (0.36) | KLKB1HPGDMETTL3KDM4EALDH1A1 | |
| SCHEMBL23530741 | 0.82 | KCNN3 (0.35) | KLKB1KDM4EALDH1A1 | |
| SCHEMBL23530958 | 0.82 | KLKB1 (0.35) | KLKB1METTL3 | |
| SCHEMBL23530932 | 0.81 | RBP4 (0.33) | KLKB1HPGDMETTL3KDM4EALDH1A1 | |
| SCHEMBL23531012 | 0.80 | KLKB1 (0.34) | KLKB1HPGDMETTL3KDM4EALDH1A1 | |
| SCHEMBL23530805 | 0.80 | KDM4E (0.49) | HPGDMETTL3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021122745-A1 | 4-[[(7-AMINOPYRAZOLO[1,5-A]PYRIMIDIN-5-YL)AMINO]METHYL]PIPERIDIN-3-OL COMPOUNDS AND THEIR THERAPEUTIC USE | Carrick Therapeutics Limited (IE) | 2021-06-24 | — | — | WO | disclosed |