Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | PDE8A | O60658 | 3/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23558168 | 0.79 | GRIN2B (0.41) | EGLN1HTR6RPS6KA5TLR7 | |
| SCHEMBL8669239 | 0.76 | HTR6 (0.59) | EGLN1HTR6LMNACYP11B1CYP11B2 | |
| SCHEMBL3449511 | 0.73 | RPS6KA5 (0.41) | EGLN1HTR6RPS6KA5AHCYLMNA | |
| SCHEMBL30881405 | 0.70 | L3MBTL1 (0.56) | LMNACYP11B2SMN1; SMN2 | |
| SCHEMBL29424873 | 0.70 | EGLN1 (0.44) | EGLN1HTR6AHCYCYP11B1CYP11B2 | |
| SCHEMBL22533661 | 0.70 | EGLN1 (0.44) | EGLN1HTR6AHCYCYP11B1CYP11B2 | |
| SCHEMBL23557919 | 0.69 | GRIN1 (0.36) | TLR7 | |
| SCHEMBL23531695 | 0.69 | EGLN1 (0.48) | EGLN1AHCYLMNAHDAC6 | |
| SCHEMBL23531728 | 0.69 | LMNA (0.45) | LMNAHTT | |
| SCHEMBL23531701 | 0.68 | CYP17A1 (0.42) | EGLN1HTR6RPS6KA5AHCYYTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077323-A1 | OGA INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2022-10-26 | — | — | EP | disclosed |
| CN-114867725-A | OGA inhibitor compounds | 詹森药业有限公司 | 2022-08-05 | — | — | CN | disclosed |
| WO-2021123294-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021123294-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |