Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932087 | 1.00 | CXCR4 (0.49) | CXCR4ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL23536063 | 0.89 | CXCR4 (0.47) | CXCR4ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL29772887 | 0.79 | LMNA (0.46) | ALDH1A1TSHRL3MBTL1MAPTNPSR1 | |
| SCHEMBL24628362 | 0.79 | LMNA (0.46) | ALDH1A1TSHRL3MBTL1MAPTNPSR1 | |
| SCHEMBL29931755 | 0.78 | CXCR4 (0.47) | CXCR4ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL12000243 | 0.76 | DRD4 (0.64) | ALDH1A1L3MBTL1MAPTNPSR1TDP1 | |
| SCHEMBL23535979 | 0.76 | CXCR4 (0.45) | CXCR4ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL29931875 | 0.76 | CXCR4 (0.45) | CXCR4ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL6269637 | 0.75 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL23536152 | 0.74 | LMNA (0.40) | ALDH1A1TSHRL3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |