Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867485 | 1.00 | OPRL1 (0.37) | OPRL1GRM2DRD4GPBAR1MEN1 | |
| SCHEMBL23535993 | 0.86 | GPR55 (0.38) | GRM2MEN1KMT2A | |
| SCHEMBL28867507 | 0.83 | OPRL1 (0.37) | OPRL1GRM2DRD4GPBAR1MEN1 | |
| SCHEMBL23536038 | 0.83 | OPRL1 (0.37) | OPRL1GRM2DRD4GPBAR1MEN1 | |
| SCHEMBL29931842 | 0.83 | MEN1 (0.33) | OPRL1MEN1KMT2A | |
| SCHEMBL29931988 | 0.79 | SMN1; SMN2 (0.36) | OPRL1GRM2 | |
| SCHEMBL23536112 | 0.78 | POLB (0.42) | GRM2MEN1KMT2A | |
| SCHEMBL29948574 | 0.78 | POLB (0.42) | GRM2MEN1KMT2A | |
| SCHEMBL23536205 | 0.77 | HTR1A (0.51) | — | |
| SCHEMBL29932303 | 0.77 | HTR1A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |