Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948480 | 1.00 | GPR55 (0.38) | GPR55CNR1SLC9A1TP53SMN1; SMN2 | |
| SCHEMBL23536117 | 0.79 | POLB (0.41) | GPR55CNR1TP53SMN1; SMN2HTT | |
| SCHEMBL29931921 | 0.79 | POLB (0.41) | GPR55CNR1TP53SMN1; SMN2HTT | |
| SCHEMBL23536363 | 0.79 | MCOLN2 (0.48) | SMN1; SMN2HTTALDH1A1KMT2APOLB | |
| SCHEMBL29932099 | 0.77 | SMN1; SMN2 (0.40) | GPR55CNR1SLC9A1TP53SMN1; SMN2 | |
| SCHEMBL23536029 | 0.77 | SMN1; SMN2 (0.40) | GPR55CNR1SLC9A1TP53SMN1; SMN2 | |
| SCHEMBL29931867 | 0.77 | TSHR (0.39) | GPR55CNR1TP53SMN1; SMN2HTT | |
| SCHEMBL23536124 | 0.77 | TSHR (0.39) | GPR55CNR1TP53SMN1; SMN2HTT | |
| SCHEMBL23535984 | 0.77 | HTR1A (0.42) | GPR55CNR1TP53SMN1; SMN2HTT | |
| SCHEMBL29932077 | 0.77 | HTR1A (0.42) | GPR55CNR1TP53SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |