Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 5/20 | 0.36 |
| ▸ | HTR1D | P28221 | 4/20 | 0.36 |
| ▸ | HTR1B | P28222 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | CCR2 | P41597 | 5/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536643 | 1.00 | HTR1F (0.36) | HTR1FHTR1DHTR1BHTR1AGPR119 | |
| SCHEMBL23536664 | 0.81 | GRM4 (0.38) | GPR119 | |
| SCHEMBL23536547 | 0.79 | PDE10A (0.37) | HTR1FHTR1DHTR1BHTR1ACCR2 | |
| SCHEMBL23536580 | 0.78 | CTSS (0.39) | HTR1DHTR1BGPR119CCR2HTR6 | |
| SCHEMBL23536621 | 0.77 | PDE10A (0.38) | HTR1FHTR1DHTR1BHTR1ACCR2 | |
| SCHEMBL23536730 | 0.75 | HTR1F (0.40) | HTR1FHTR1DHTR1BHTR1ACCR2 | |
| SCHEMBL23536638 | 0.74 | PDE10A (0.42) | HTR1FHTR1DHTR1BHTR1ACCR2 | |
| SCHEMBL23536526 | 0.74 | FLT3 (0.34) | HTR1FSSTR3 | |
| SCHEMBL2346187 | 0.73 | HTR2C (0.58) | HTR1FHTR1DHTR1BHTR1ACCR2 | |
| SCHEMBL30909178 | 0.72 | HTR1F (0.65) | HTR1FHTR1DHTR1BHTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |