Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 15/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | ITK | Q08881 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536645 | 0.81 | HTR1F (0.36) | GPR119 | |
| SCHEMBL23536643 | 0.81 | HTR1F (0.36) | GPR119 | |
| SCHEMBL23536569 | 0.75 | GRM4 (0.39) | GRM4CYP1A2ITK | |
| SCHEMBL23536710 | 0.74 | ITK (0.39) | GRM4ITK | |
| SCHEMBL23536526 | 0.68 | FLT3 (0.34) | GRM4CYP1A2 | |
| SCHEMBL23536580 | 0.64 | CTSS (0.39) | CYP1A2GPR119 | |
| SCHEMBL26745353 | 0.61 | DDB1 (0.40) | GRM4CYP1A2ITK | |
| SCHEMBL23570073 | 0.60 | GPR119 (0.34) | GPR119 | |
| SCHEMBL24198014 | 0.59 | GRM4 (0.50) | GRM4ITK | |
| SCHEMBL254887 | 0.59 | GRM4 (0.54) | GRM4ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |