Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536839 | 0.85 | HSD17B10 (0.39) | HTR6MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL23536635 | 0.80 | HSD17B10 (0.48) | HTR6MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL23536682 | 0.78 | HTR6 (0.34) | HTR6KMT2ACYP2D6 | |
| SCHEMBL23536533 | 0.75 | HTR6 (0.40) | HTR6MEN1KMT2AL3MBTL1 | |
| SCHEMBL23536644 | 0.74 | GPR119 (0.37) | GPR119 | |
| SCHEMBL23536556 | 0.74 | GPR119 (0.37) | GPR119 | |
| SCHEMBL23536557 | 0.74 | GPR119 (0.37) | GPR119 | |
| SCHEMBL23536596 | 0.74 | SLC6A2 (0.39) | HTR6MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL23536524 | 0.74 | SMN1; SMN2 (0.36) | HTR6ALDH1A1CYP3A4SMN1; SMN2CYP2D6 | |
| SCHEMBL29932249 | 0.72 | MCOLN3 (0.46) | MEN1KMT2AALDH1A1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |