Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319482 | 0.84 | LOXL2 (0.48) | MAOBLOXL2 | |
| SCHEMBL30335660 | 0.84 | LOXL2 (0.48) | MAOBLOXL2 | |
| SCHEMBL27868543 | 0.81 | GRM5 (0.33) | — | |
| SCHEMBL1014548 | 0.79 | TAAR1 (0.60) | TAAR1MAOBLOXL2 | |
| SCHEMBL20646934 | 0.78 | TSHR (0.44) | — | |
| SCHEMBL23536729 | 0.77 | TAAR1 (0.46) | TAAR1LOXL2ADRA2C | |
| SCHEMBL16955446 | 0.77 | PGR (0.35) | — | |
| SCHEMBL1469433 | 0.77 | TAAR1 (0.46) | TAAR1MAOB | |
| Hydrochloric Acid SCHEMBL2211247 | 0.77 | TAAR1 (0.58) | TAAR1MAOBLOXL2 | |
| SCHEMBL5222310 | 0.76 | IDO1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076418-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021127429-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |