Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019992 | 0.85 | KDM4E (0.43) | IDO1KDM4ETDP1CYP11B1CYP11B2 | |
| SCHEMBL1014548 | 0.83 | TAAR1 (0.60) | TAAR1MAOBIDO1DAOHTR2A | |
| SCHEMBL8657492 | 0.81 | KDM4E (0.43) | IDO1KDM4ETDP1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL2211247 | 0.81 | TAAR1 (0.58) | TAAR1MAOBIDO1KDM4ETDP1 | |
| SCHEMBL23536734 | 0.77 | TAAR1 (0.46) | TAAR1MAOB | |
| SCHEMBL25808872 | 0.76 | KDM4E (0.37) | IDO1KDM4ETDP1CYP11B1CYP11B2 | |
| SCHEMBL14431663 | 0.74 | KDM4E (0.38) | IDO1KDM4ETDP1CYP11B1CYP11B2 | |
| SCHEMBL19546176 | 0.73 | GPR84 (0.45) | KDM4EHTR2AHTR2C | |
| SCHEMBL10546321 | 0.73 | MEN1 (0.52) | TAAR1IDO1TDP1CYP11B1DAO | |
| SCHEMBL20576683 | 0.72 | KDM4E (0.37) | IDO1KDM4ETDP1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071134-A1 | 2-(AMINO-SUBSTITUTED)-4-ARYL PYRIMIDINES AND RELATED COMPOUNDS USEFUL FOR TREATING INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071134-A1 | 2-(AMINO-SUBSTITUTED)-4-ARYL PYRIMIDINES AND RELATED COMPOUNDS USEFUL FOR TREATING INFLAMMATORY DISEASES | PRKCZ, PRKCQ, PRKCE | TAAR1 2694/4885MAOB 2252/4885IDO1 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.