Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 3/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356296 | 0.80 | ALDH1A1 (0.33) | L3MBTL1 | |
| SCHEMBL6602979 | 0.77 | — | — | |
| SCHEMBL29219229 | 0.76 | — | — | |
| SCHEMBL1427291 | 0.76 | ACHE (0.35) | — | |
| SCHEMBL28394743 | 0.75 | ACHE (0.35) | — | |
| SCHEMBL7244739 | 0.72 | GAA (0.44) | KMT2A | |
| SCHEMBL508861 | 0.70 | NPC1 (0.44) | KMT2AL3MBTL1 | |
| SCHEMBL692875 | 0.70 | — | — | |
| SCHEMBL561256 | 0.69 | — | — | |
| SCHEMBL23080822 | 0.68 | GAA (0.39) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284380-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | US | disclosed |
| EP-2914587-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014067962-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2014-05-08 | — | — | WO | disclosed |
| WO-2014060381-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | disclosed |
| EP-2536714-A2 | A NOVEL 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | Il-Dong Pharm. Co., Ltd. (KR) | 2012-12-26 | — | — | EP | disclosed |
| US-20120309750-A1 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | ILDONG PHARM CO., LTD. (KR) | 2012-12-06 | — | — | US | disclosed |
| CN-102753546-A | 5-membered heterocyclic derivatives and process for producing the same | ILDONG PHARM CO LTD | 2012-10-24 | — | — | CN | disclosed |
| WO-2011102660-A2 | A NOVEL 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | ILDONG PHARM CO., LTD. (KR) | 2011-08-25 | — | — | WO | disclosed |
| EP-1123296-B1 | PYRAZOLOPYRIMIDINONE cGMP PDE5 INHIBITORS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | PFIZER LTD (GB) | 2003-09-17 | — | — | EP | disclosed |
| US-6333330-B1 | Pyrazolopyrimidinone CGMP PDE5 inhibitors for the treatment of sexual dysfunction | PFIZER INC. | 2001-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284380-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, KEAP1, NISCH | KMT2A 1280/4885L3MBTL1 104/4885JAK3 4218/4885 |
| US-20120309750-A1 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | CYP3A5, UGT2B7, UGT1A7 | KMT2A 3539/4885L3MBTL1 4630/4885JAK3 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.