SCHEMBL2354259

SCHEMBL2354259

CCCCC(OC(C)C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.48
MAPK1 P28482 1/20 0.48
ACE2 Q9BYF1 1/20 0.42
GPR84 Q9NQS5 3/20 0.42
CA1 P00915 3/20 0.42
FFAR1 O14842 1/20 0.42
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
MAPT P10636 1/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
PTGES O14684 1/20 0.40
ALOX5 P09917 1/20 0.40
PPARG P37231 1/20 0.40
LMNA P02545 2/20 0.39
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26940474 1.00 CA2 (0.48) CA2MAPK1ACE2GPR84CA1
SCHEMBL27670297 0.92 GPR84 (0.53) CA2ACE2GPR84CA1FFAR1
SCHEMBL29165517 0.92 GPR84 (0.53) CA2ACE2GPR84CA1FFAR1
SCHEMBL27525393 0.90 GPR84 (0.52) CA2ACE2GPR84CA1FFAR1
SCHEMBL27523512 0.90 GPR84 (0.52) CA2ACE2GPR84CA1FFAR1
SCHEMBL27497981 0.90 GPR84 (0.52) CA2ACE2GPR84CA1FFAR1
SCHEMBL27335805 0.90 GPR84 (0.52) CA2ACE2GPR84CA1FFAR1
SCHEMBL2573721 0.89 CA2 (0.54) CA2MAPK1ACE2GPR84CA1
SCHEMBL2232093 0.86 CHRM1 (0.48) CA2MAPK1ACE2GPR84SLC1A3
SCHEMBL26940421 0.86 CHRM1 (0.48) CA2MAPK1ACE2GPR84SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127733-A1 TOXIC ALDEHYDE RELATED DISEASES AND TREATMENT ALDEYRA THERAPEUTICS, INC. 2025-04-24 US disclosed
US-11701331-B2 Toxic aldehyde related diseases and treatment ALDEYRA THERAPEUTICS, INC. (US) 2023-07-18 US disclosed
US-20210275469-A1 TOXIC ALDEHYDE RELATED DISEASES AND TREATMENT ALDEYRA THERAPEUTICS, INC. 2021-09-09 US disclosed
US-11007157-B2 Toxic aldehyde related diseases and treatment ALDEYRA THERAPEUTICS, INC. (US) 2021-05-18 US disclosed
US-10588874-B2 Toxic aldehyde related diseases and treatment ALDEYRA THERAPEUTICS, INC. (US) 2020-03-17 US disclosed
US-20190247334-A1 TOXIC ALDEHYDE RELATED DISEASES AND TREATMENT ALDEXA THERAPEUTICS, INC. 2019-08-15 US disclosed
EP-2348833-A2 LIQUID AQUEOUS CROP PROTECTION FORMULATIONS BASF SE (DE) 2011-08-03 EP disclosed
CN-1950459-B Curable composition improved in solidification and adhesiveness KANEGAFUCHI CHEMICAL IND 2011-05-25 CN disclosed
WO-2010040834-A2 LIQUID AQUEOUS CROP PROTECTION FORMULATIONS BASF SE (DE) 2010-04-15 WO disclosed
CN-1950459-A Curable composition improved in solidification and adhesiveness KANEGAFUCHI CHEMICAL IND (JP) 2007-04-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210275469-A1 TOXIC ALDEHYDE RELATED DISEASES AND TREATMENT ALDH1A2, ALDH2, ALDH1A1 CA2 2456/4885MAPK1 4021/4885ACE2 390/4885
US-20190247334-A1 TOXIC ALDEHYDE RELATED DISEASES AND TREATMENT ALDH1A2, ALDH2, ALDH1A1 CA2 2456/4885MAPK1 4021/4885ACE2 390/4885
US-11007157-B2 Toxic aldehyde related diseases and treatment ALDH1A2, ALDH2, ALDH1A1 CA2 2456/4885MAPK1 4021/4885ACE2 390/4885
US-10588874-B2 Toxic aldehyde related diseases and treatment ALDH1A2, ALDH2, ALDH1A1 CA2 2456/4885MAPK1 4021/4885ACE2 390/4885
US-20250127733-A1 TOXIC ALDEHYDE RELATED DISEASES AND TREATMENT ALDH1A2, ALDH2, ALDH1A1 CA2 2456/4885MAPK1 4021/4885ACE2 390/4885
US-11701331-B2 Toxic aldehyde related diseases and treatment ALDH1A2, ALDH2, ALDH1A1 CA2 2456/4885MAPK1 4021/4885ACE2 390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.