SCHEMBL25944773

SCHEMBL25944773

C#CCC(=O)NCCOCCC(=O)NCCCCC(NC(C)C)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.37
▸ ALB P02768 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ FOLH1 Q04609 2/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25944734 0.88 ALB (0.38) ALBL3MBTL1FOLH1SIRT5MEN1
SCHEMBL23544192 0.83 GLP1R (0.53) GLP1R
SCHEMBL23330799 0.82 ALB (0.41) ALBL3MBTL1FOLH1SIRT5MEN1
SCHEMBL26225643 0.79 GLP1R (0.38) GLP1RALBL3MBTL1FOLH1SIRT5
SCHEMBL25944862 0.79 ALB (0.36) GLP1RALBSIRT5
SCHEMBL23544195 0.77 GLP1R (0.61) GLP1RFOLH1
SCHEMBL8119857 0.76 GLP1R (0.44) GLP1RALBFOLH1SIRT5TSHR
SCHEMBL22423516 0.76 GLP1R (0.54) GLP1R
SCHEMBL22423517 0.76 GLP1R (0.49) GLP1RFOLH1
SCHEMBL23589786 0.75 ALB (0.39) ALBL3MBTL1FOLH1SIRT5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331801-A1 IL-2R-BETA-GAMMA BINDING COMPOUNDS MEDIKINE, INC. (US) 2023-10-19 — — US disclosed
US-11718654-B2 IL-2R-βγ binding compounds MEDIKINE, INC. (US) 2023-08-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331801-A1 IL-2R-BETA-GAMMA BINDING COMPOUNDS IL2RA, IL2, IL15RA GLP1R 317/4885ALB 1363/4885L3MBTL1 3723/4885
US-11718654-B2 IL-2R-βγ binding compounds IL2RA, IL2, IL1RN GLP1R 306/4885ALB 2282/4885L3MBTL1 3752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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