SCHEMBL235469

SCHEMBL235469

C=C(C)C(=O)OC[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.37
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL666441 0.92 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL3503300 0.89 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL80190 0.85 THRB (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2240698 0.84 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL231818 0.84 THRB (0.42) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL237865 0.84 TSHR (0.49) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL237187 0.84 TSHR (0.49) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL72841 0.81 TSHR (0.59) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1805670 0.80 ALDH1A1 (0.46) TSHRALDH1A1
SCHEMBL23002885 0.80 THRB (0.41) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1298166-B1 RUBBER COMPOSITION JSR CORP (JP) 2007-02-21 EP claimed
US-6699935-B2 A CROSSLINKED RUBBER PARTICLES CONTAINING CONJUGATED DIENE MONOMER, AROMATIC VINYL MONOMER AND MONOMER WITH AT LEAST TWO POLYMERIZABLE UNSATURATED GROUPS DISPERSED IN A CONJUGATED DIENE/AROMATIC VINYL COPOLYMER; RESIST TO ROLLING, SKID, WEAR JSR CORPORATION (JP) 2004-03-02 US claimed
US-6653404-B2 Melt processability; dimensional stability JSR CORPORATION (JP) 2003-11-25 US claimed
EP-1298166-A1 RUBBER COMPOSITION JSR Corporation (JP) 2003-04-02 EP claimed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US claimed
EP-4349902-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-04-10 EP disclosed
WO-2022254751-A1 RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2022-12-08 WO disclosed
CN-110408206-B Polyamic acid resin composition, method for preparing the same, and film formed from the same 无锡创彩光学材料有限公司 2022-05-17 CN disclosed
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
EP-3730547-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2020-10-28 EP disclosed
EP-3725836-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2020-10-21 EP disclosed
EP-3406664-B1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORP (JP) 2020-08-05 EP disclosed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US disclosed
EP-1152030-A2 Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers JSR Corporation (JP) 2001-11-07 EP disclosed
EP-1149866-A2 Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers JSR Corporation (JP) 2001-10-31 EP disclosed
EP-1149867-A2 Crosslinked rubber particles and rubber compositions JSR Corporation (JP) 2001-10-31 EP disclosed
EP-0604677-B1 Method of making coated shaped articles MITSUBISHI RAYON CO (JP) 1999-08-11 EP disclosed
US-5470616-A Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1995-11-28 US disclosed
US-4081421-A Curable resin composition for abrasion-resistant coating JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1978-03-28 US disclosed
US-4029842-A POLYMETHYL METHACRYLATE COATED AND OVERCOATED WITH TRIALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-06-14 US disclosed