SCHEMBL666441

SCHEMBL666441

C=C(C)C(=O)OC[Si](C)(OCCC)OCCC.C=C(C)C(=O)OC[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.41
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237865 0.94 TSHR (0.49) TSHRTHRBALDH1A1
SCHEMBL235469 0.92 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL5699018 0.84 TSHR (0.54) TSHRTHRBALDH1A1
SCHEMBL3503300 0.82 TSHR (0.56) TSHRTHRBALDH1A1
SCHEMBL237187 0.80 TSHR (0.49) TSHRTHRBALDH1A1
SCHEMBL9757143 0.80 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL143881 0.80 THRB (0.48) TSHRTHRBALDH1A1
SCHEMBL229906 0.79 ALDH1A1 (0.42) TSHRTHRBALDH1A1
SCHEMBL2246405 0.79 TSHR (0.51) TSHRTHRBALDH1A1
SCHEMBL80190 0.78 THRB (0.50) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US disclosed
US-20120045586-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS AND THE USE THEREOF BASF COATINGS GMBH (DE) 2012-02-23 US disclosed