Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908201 | 0.90 | ACHE (0.53) | ACHE | |
| SCHEMBL18009557 | 0.74 | ACHE (0.53) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL14156890 | 0.72 | ACHE (0.53) | ACHE | |
| SCHEMBL3658017 | 0.72 | ACHE (0.61) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL20692255 | 0.72 | ACHE (0.59) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL29621066 | 0.72 | ACHE (0.61) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL8099829 | 0.72 | ACHE (0.69) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL8091521 | 0.72 | ACHE (0.69) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL6250546 | 0.71 | BRD4 (0.32) | — | |
| SCHEMBL19290149 | 0.71 | RARA (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003743-B2 | Low elastic modulus, high molecular weight; high yield; polymerization catalysts such as dimethylsilanediyl{5-(1,1,3,3,6-pentamethyl-1,2,3,5-tetrahydroindacenyl)-7-(2,5-dimethyl-cyclopenta[1,2-b:4,3-b']-dithiophene)}zirconium dichloride | Basell Poliolefine Italia, s.r.l. (IT) | 2011-08-23 | — | — | US | disclosed |
| US-8003743-B2 | Low elastic modulus, high molecular weight; high yield; polymerization catalysts such as dimethylsilanediyl{5-(1,1,3,3,6-pentamethyl-1,2,3,5-tetrahydroindacenyl)-7-(2,5-dimethyl-cyclopenta[1,2-b:4,3-b']-dithiophene)}zirconium dichloride | Basell Poliolefine Italia, s.r.l. (IT) | 2011-08-23 | — | — | US | disclosed |
| US-8003743-B2 | Low elastic modulus, high molecular weight; high yield; polymerization catalysts such as dimethylsilanediyl{5-(1,1,3,3,6-pentamethyl-1,2,3,5-tetrahydroindacenyl)-7-(2,5-dimethyl-cyclopenta[1,2-b:4,3-b']-dithiophene)}zirconium dichloride | Basell Poliolefine Italia, s.r.l. (IT) | 2011-08-23 | — | — | US | disclosed |
| US-7589160-B2 | homopolymerizing butene/1-/ or copolymerizing with ethylene or propylene in presnece of a metallocene catalyst such as dimethyl-bis-(2,5,5,7,7-pentamethyl-1,5,6,7-tetrahydro-s-indacen-1-yl)-silane, an alumoxane or aluminum compound ( triisobutylaluminum) | BASELL POLYOLEFINE GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-20080139762-A1 | Metallocene Compounds, Ligands Used in Their Preparation, Preparation of 1-Butene Polymers and 1-Butene Polymers Therefrom | BASELL POLYOLEFINE GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080139762-A1 | Metallocene Compounds, Ligands Used in Their Preparation, Preparation of 1-Butene Polymers and 1-Butene Polymers Therefrom | BASELL POLYOLEFINE GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080139762-A1 | Metallocene Compounds, Ligands Used in Their Preparation, Preparation of 1-Butene Polymers and 1-Butene Polymers Therefrom | BASELL POLYOLEFINE GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| EP-1567565-B1 | PROCESS FOR PREPARING 1-BUTENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2008-01-09 | — | — | EP | disclosed |
| EP-1765886-A1 | METALLOCENE COMPOUNDS, LIGANDS USED IN THEIR PREPARATION, PREPARATION OF 1-BUTENE POLYMERS AND 1-BUTENE POLYMERS THEREFROM | Basell Polyolefine GmbH (DE) | 2007-03-28 | — | — | EP | disclosed |
| US-20060052553-A1 | Process for preparing 1-butene polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
| WO-2006005648-A1 | METALLOCENE COMPOUNDS, LIGANDS USED IN THEIR PREPARATION, PREPARATION OF 1-BUTENE POLYMERS AND 1-BUTENE POLYMERS THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2006-01-19 | — | — | WO | disclosed |
| EP-1567565-A1 | PROCESS FOR PREPARING 1-BUTENE POLYMERS | Basell Polyolefine GmbH (DE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050724-A1 | PROCESS FOR PREPARING 1-BUTENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139762-A1 | Metallocene Compounds, Ligands Used in Their Preparation, Preparation of 1-Butene Polymers and 1-Butene Polymers Therefrom | CHRM1, B2M, CHRM2 | ACHE 2161/4885KDM4E 4312/4885MEN1 809/4885 |
| US-20060052553-A1 | Process for preparing 1-butene polymers | OR10J3, C1R, LTB4R | ACHE 2646/4885KDM4E 2031/4885MEN1 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.