SCHEMBL2354995

SCHEMBL2354995

CC(C)(C)COc1ccccc1O[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
RIPK1 Q13546 2/20 0.35
KDM4E B2RXH2 1/20 0.34
NUDT1 P36639 1/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
GABRB2 P47870 1/20 0.34
GABRA4 P48169 1/20 0.34
GABRE P78334 1/20 0.34
GABRA6 Q16445 1/20 0.34
GABRG1 Q8N1C3 1/20 0.34
GABRG3 Q99928 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13449767 0.89 KDM4E (0.41) PIM1PIM2RIPK1KDM4ENUDT1
SCHEMBL5794634 0.81 CA12 (0.56) L3MBTL1MAPTLMNAPOLBSMN1; SMN2
SCHEMBL28553583 0.81 PIM1 (0.37) PIM1PIM2RIPK1KDM4ENUDT1
SCHEMBL26825677 0.81 ALDH1A1 (0.52) KDM4EL3MBTL1MAPTNPSR1GLA
SCHEMBL10064784 0.79 L3MBTL1 (0.49) L3MBTL1MAPTSMN1; SMN2TDP1SSTR1
SCHEMBL16744336 0.79 PIM1 (0.36) PIM1PIM2RIPK1KDM4ENUDT1
SCHEMBL8083251 0.77 ALDH1A1 (0.48) KDM4EL3MBTL1LMNAGLAALDH1A1
SCHEMBL12250933 0.76 MAPT (0.58) L3MBTL1MAPTGAATDP1
SCHEMBL1609080 0.76 ALDH1A1 (0.56) KDM4EL3MBTL1MAPTLMNAGAA
SCHEMBL13050673 0.75 CYP1A2 (0.51) KDM4EL3MBTL1MAPTLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
EP-3268353-B1 PYRAZOLYL DERIVATIVES AS PEST CONTROL AGENTS BAYER ANIMAL HEALTH GMBH (DE) 2020-09-09 EP disclosed
EP-3157913-B1 PYRAZOLYL TRIAZOLYL PYRIDINES AS PESTICIDE BAYER ANIMAL HEALTH GMBH (DE) 2019-04-17 EP disclosed
EP-3089972-B1 NOVEL PYRAZOLE HETEROARYLAMIDES AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2018-05-16 EP disclosed
EP-3268353-A1 PYRAZOLYL-DERIVATIVES AS PEST CONTROL AGENTS Bayer Animal Health GmbH (DE) 2018-01-17 EP disclosed
EP-2953942-B1 HALOGEN-SUBSTITUTED PYRAZOLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2017-10-25 EP disclosed
EP-2794573-B1 NOVEL INSECTICIDAL AROMATIC AMIDES BAYER IP GMBH (DE) 2017-08-30 EP disclosed
EP-2964631-B1 HALOGEN-SUBSTITUTED N-[3-(1H-PYRAZOL-4-YL)PHENYLMETHYL]-SULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES FOR USE IN CROP PROTECTION IN VETERINARY MEDICINE AND IN MATERIAL PROTECTION BAYER ANIMAL HEALTH GMBH (DE) 2017-08-30 EP disclosed
EP-3157913-A1 PYRAZOLYL-TRIAZOLYL-PYRIDINES AS PEST-CONTROL AGENTS Bayer Animal Health GmbH (DE) 2017-04-26 EP disclosed
EP-2964632-B1 HALOGEN SUBSTITUTED 1H-PYRAZOLE DERIVATIVES AS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2016-12-14 EP disclosed
EP-2686303-A1 N-(3-CARBAMOYLPHENYL)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS Bayer Intellectual Property GmbH (DE) 2014-01-22 EP disclosed
WO-2013092522-A1 NOVEL INSECTICIDAL AROMATIC AMIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-27 WO disclosed
WO-2012126766-A1 N-(3-CARBAMOYLPHENYL)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AG (DE) 2012-09-27 WO disclosed
EP-2352723-A2 HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES Bayer CropScience AG (DE) 2011-08-10 EP disclosed
EP-2054427-B1 AVERMECTIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-07-14 EP disclosed
WO-2010051926-A2 NEW HALOGEN-SUBSTITUTED BONDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-05-14 WO disclosed
EP-2184273-A1 Halogen substituted compounds as pesticides Bayer CropScience AG (DE) 2010-05-12 EP disclosed
WO-2009141096-A1 SUBSTITUTED SPIRO-ISOXAZOLINES BAYER CROPSCIENCE AG (DE) 2009-11-26 WO disclosed
EP-1896480-A1 CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS Bayer CropScience Aktiengesellschaft (DE) 2008-03-12 EP disclosed
WO-2006136309-A1 CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2006-12-28 WO disclosed