Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 14/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355589 | 0.87 | ADRA1D (0.40) | ADRA1DCA1CA2ADRA1AADRA1B | |
| SCHEMBL2355164 | 0.81 | CA1 (0.41) | ADRA1DCA1CA2KDM1A | |
| SCHEMBL2354707 | 0.81 | CA1 (0.41) | ADRA1DCA1CA2GRIA1GRIA2 | |
| SCHEMBL2355163 | 0.80 | ADRA1D (0.32) | ADRA1D | |
| SCHEMBL20992167 | 0.79 | ADRA1D (0.46) | ADRA1DCA1CA2ADRA1AADRA1B | |
| SCHEMBL17050355 | 0.79 | ADRA1D (0.46) | ADRA1DCA1CA2ADRA1AADRA1B | |
| SCHEMBL17033295 | 0.79 | CA1 (0.56) | ADRA1DCA1CA2ADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL1004820 | 0.77 | ADRA1D (0.48) | ADRA1DCA1CA2ADRA1AADRA1B | |
| SCHEMBL2357167 | 0.76 | ADRA1D (0.37) | ADRA1D | |
| SCHEMBL2352846 | 0.76 | ADRA1D (0.42) | ADRA1DVEGFAEPAS1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |