SCHEMBL2355840

SCHEMBL2355840

Cc1nccc(CO)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.52
HPGD P15428 4/20 0.52
ALDH1A1 P00352 3/20 0.52
HSD17B10 Q99714 1/20 0.52
LMNA P02545 6/20 0.50
PDXK O00764 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
AOX1 Q06278 1/20 0.50
TRIM24 O15164 1/20 0.49
TRIM33 Q9UPN9 1/20 0.49
TP53 P04637 1/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
HTT P42858 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
CYP2A6 P11509 1/20 0.38
GAA P10253 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28811005 0.98 TRIM24 (0.51) KDM4EHPGDALDH1A1HSD17B10LMNA
SCHEMBL23193106 0.83 GABRA1 (0.48) KDM4EHPGDALDH1A1HSD17B10LMNA
SCHEMBL4795960 0.80 KDM4E (0.41) KDM4EHPGDALDH1A1HSD17B10LMNA
Hydrochloric Acid SCHEMBL21439797 0.79 TRIM24 (0.39) KDM4EHPGDALDH1A1HSD17B10LMNA
SCHEMBL3679899 0.78 KDM4E (0.47) KDM4EHPGDALDH1A1HSD17B10LMNA
SCHEMBL27643119 0.78 KDM4E (0.35) KDM4EHPGDALDH1A1HSD17B10LMNA
SCHEMBL29829837 0.77 KDM4E (0.47) KDM4EHPGDALDH1A1HSD17B10LMNA
SCHEMBL28714994 0.77 KDM4E (0.39) KDM4EHPGDALDH1A1HSD17B10LMNA
SCHEMBL29439832 0.77 KDM4E (0.39) KDM4EHPGDALDH1A1HSD17B10LMNA
SCHEMBL6035481 0.76 KDM4E (0.43) KDM4EHPGDALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1087367-A Structural adhesive composition with high temperature resistance LORD CORP (US) 1994-06-01 CN claimed
CN-118102892-A Composition comprising a nutrient and a taste modifier 弗门尼舍有限公司 2024-05-28 CN disclosed
CN-112839638-B Method for preparing sustained release multi-unit oral dosage form of doxylamine succinate and pyridoxine hydrochloride 意大发马克股份公司 2023-12-19 CN disclosed
CN-115697311-A Modified release multiple unit oral dosage form of doxylamine succinate and pyridoxine hydrochloride and preparation method thereof 意大发马克股份公司 2023-02-03 CN disclosed
CN-114423421-A Preparation of PSMA developer 透明医药有限公司 2022-04-29 CN disclosed
CN-112839638-A Method for preparing a sustained release multiple unit oral dosage form of doxylamine succinate and pyridoxine hydrochloride 益利巴萨妇科股份公司 2021-05-25 CN disclosed
CN-110869024-A Multi-biological agents and methods of use thereof 旗舰创业创新五公司 2020-03-06 CN disclosed
EP-2676680-A1 Use of hydrophobin polypeptides as penetration enhancers BASF SE (DE) 2013-12-25 EP disclosed
EP-2344117-A2 USE OF HYDROPHOBIN FOR NON-PERMANENT DYEING OF KERATIN BASF SE (DE) 2011-07-20 EP disclosed
EP-2200651-A2 USE OF HYDROPHOBIN POLYPEPTIDES AS PENETRATION ENHANCERS BASF SE (DE) 2010-06-30 EP disclosed
CN-1067096-C Structural adhesive composition having high temperature resistance LORD CORP (US) 2001-06-13 CN disclosed
CN-1087367-A Structural adhesive composition with high temperature resistance LORD CORP (US) 1994-06-01 CN disclosed
US-4546106-A ANTIARTHRITIC AGENTS MERCK & CO., INC. (US) 1985-10-08 US disclosed
US-4472387-A 5-HYDROXYTRYPTOPHAN OR ESTER, NITROGEN HETEROCYCLE PANMEDICA S.A. (FR) 1984-09-18 US disclosed
US-4355034-A Ethenyl derivatives of mercaptoalkylpyridines as anti-inflammatory agents MERCK & CO., INC. (US) 1982-10-19 US disclosed
US-4217352-A ANTIARTHRITIC AGENT MERCK & CO., INC. (US) 1980-08-12 US disclosed
US-4189487-A Use of pyridine aldehydes for the prevention and treatment of acne vulgaris KLOSA JOSEF (DE) 1980-02-19 US disclosed
US-4144342-A ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS MERCK & CO., INC. (US) 1979-03-13 US disclosed
US-4061759-A ANTIINFLAMMATORY, ARTHRITIS MERCK & CO., INC. (US) 1977-12-06 US disclosed
US-4053606-A ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS MERCK & CO., INC. (US) 1977-10-11 US disclosed