Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PDXK | O00764 | 2/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25652149 | 0.88 | KDM4E (0.40) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL31214305 | 0.83 | KDM4E (0.37) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL4795960 | 0.80 | KDM4E (0.41) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL305502 | 0.80 | NOS2 (0.45) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL31150926 | 0.80 | NOS2 (0.45) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL2355840 | 0.78 | KDM4E (0.52) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL23857355 | 0.77 | KDM4E (0.37) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL9846997 | 0.77 | NOS2 (0.38) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL21352029 | 0.77 | KDM4E (0.37) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL31150936 | 0.77 | KDM4E (0.41) | KDM4EHPGDALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231604-A1 | PREPARATIONS CONTAINING PYRIDOXINE AND ALPHA-HYDROXYISOCAPROIC ACID (HICA) | Northern Innovations and Formulations Corp. (CA) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009073943-A1 | PREPARATIONS CONTAINING PYRIDOXINE AND ALPHA-HYDROXYISOCAPROIC ACID (HICA) | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | WO | disclosed |