Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13674009 | 0.78 | NCF1 (0.56) | NCF1 | |
| SCHEMBL22080010 | 0.78 | ESR1 (0.32) | NCF1 | |
| SCHEMBL26059718 | 0.76 | PDK1 (0.32) | — | |
| SCHEMBL24498429 | 0.75 | L3MBTL1 (0.39) | — | |
| SCHEMBL23442240 | 0.75 | HTT (0.34) | — | |
| SCHEMBL20084193 | 0.75 | OPRK1 (0.30) | — | |
| SCHEMBL25468553 | 0.75 | — | — | |
| SCHEMBL24258358 | 0.74 | — | — | |
| SCHEMBL23489042 | 0.73 | BCHE (0.31) | — | |
| SCHEMBL26849339 | 0.72 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147329-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2022133285-A1 | MOLECULES AND METHODS RELATED TO TREATMNET OF DISORDERS ASSOCIATED WITH JAK-2 SIGNALING DYSFUNCTION | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2021127499-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2021-06-24 | — | — | WO | disclosed |