Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 6/20 | 0.47 |
| ▸ | ALPL | P05186 | 6/20 | 0.47 |
| ▸ | XIAP | P98170 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23564636 | 0.90 | ALDH1A1 (0.46) | ENPP3ALPLXIAPMAPTALDH1A1 | |
| SCHEMBL23564634 | 0.89 | ENPP3 (0.60) | ENPP3ALPLXIAPPOLBHSD17B10 | |
| SCHEMBL23564556 | 0.80 | TSHR (0.45) | ENPP3ALPLXIAPPOLBHSD17B10 | |
| SCHEMBL23564551 | 0.77 | TSHR (0.42) | ENPP3ALPLXIAPPOLBHSD17B10 | |
| SCHEMBL23564554 | 0.77 | ALDH1A1 (0.43) | ENPP3ALPLXIAPPOLBHSD17B10 | |
| SCHEMBL23564559 | 0.76 | TSHR (0.46) | ENPP3ALPLXIAPPOLBHSD17B10 | |
| SCHEMBL23564553 | 0.76 | TSHR (0.39) | ENPP3ALPLXIAPPOLBHSD17B10 | |
| SCHEMBL23564563 | 0.75 | ALDH1A1 (0.41) | ENPP3ALPLXIAPPOLBHSD17B10 | |
| SCHEMBL23564641 | 0.74 | POLB (0.41) | ENPP3ALPLXIAPPOLBHSD17B10 | |
| SCHEMBL23564547 | 0.74 | ALDH1A1 (0.43) | ENPP3ALPLXIAPALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370760-B2 | Dithioester compound | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2022-06-28 | — | — | US | disclosed |
| US-20210188780-A1 | DITHIOESTER COMPOUND | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11370760-B2 | Dithioester compound | SQOR, LANCL1, AKR1C4 | ENPP3 1752/4885ALPL 2302/4885XIAP 2275/4885 |
| US-20210188780-A1 | DITHIOESTER COMPOUND | SQOR, LANCL1, AKR1C4 | ENPP3 1561/4885ALPL 2218/4885XIAP 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.