SCHEMBL23564641

SCHEMBL23564641

Cc1cc(C)n(C(=S)SOC(C)(C)c2ccccc2)n1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
HSD17B10 Q99714 2/20 0.39
ENPP3 O14638 3/20 0.39
ALPL P05186 3/20 0.39
XIAP P98170 3/20 0.39
ALDH1A1 P00352 4/20 0.37
TP53 P04637 1/20 0.37
GAA P10253 1/20 0.36
PDE4B Q07343 2/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23564670 0.82 TSHR (0.39) POLBHSD17B10ENPP3ALPLXIAP
SCHEMBL23564635 0.74 ENPP3 (0.47) POLBHSD17B10ENPP3ALPLXIAP
SCHEMBL23564547 0.74 ALDH1A1 (0.43) ENPP3ALPLXIAPALDH1A1GAA
SCHEMBL23564551 0.71 TSHR (0.42) POLBHSD17B10ENPP3ALPLXIAP
SCHEMBL19150297 0.70 ALDH1A1 (0.46) POLBHSD17B10ENPP3ALPLXIAP
SCHEMBL4436614 0.69 TSHR (0.47) POLBENPP3ALPLXIAPALDH1A1
SCHEMBL23564556 0.69 TSHR (0.45) POLBHSD17B10ENPP3ALPLXIAP
SCHEMBL13305863 0.67 ALDH1A1 (0.47) HSD17B10ALDH1A1L3MBTL1ALOX15
SCHEMBL4436617 0.67 TSHR (0.44) POLBENPP3ALPLXIAPALDH1A1
SCHEMBL23564554 0.66 ALDH1A1 (0.43) POLBHSD17B10ENPP3ALPLXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820838-B2 Modified diene-based polymer SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-11-21 US disclosed
US-11820838-B2 Modified diene-based polymer SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-11-21 US disclosed
US-11787879-B2 Production method of modified diene-based polymer SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-10-17 US disclosed
US-11787879-B2 Production method of modified diene-based polymer SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-10-17 US disclosed
US-11370760-B2 Dithioester compound SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2022-06-28 US disclosed
US-20210188780-A1 DITHIOESTER COMPOUND SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2021-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370760-B2 Dithioester compound SQOR, LANCL1, AKR1C4 POLB 4586/4885HSD17B10 105/4885ENPP3 1752/4885
US-20210188780-A1 DITHIOESTER COMPOUND SQOR, LANCL1, AKR1C4 POLB 4654/4885HSD17B10 104/4885ENPP3 1561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.