SCHEMBL2356476

SCHEMBL2356476

C[C@H](CO)Oc1ccccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.43
DYRK2 Q92630 2/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALOX5AP P20292 4/20 0.37
FEN1 P39748 4/20 0.37
TSHR P16473 2/20 0.37
CYP1A2 P05177 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
CCR1 P32246 1/20 0.37
CCR5 P51681 1/20 0.37
CCR8 P51685 1/20 0.37
METAP1 P53582 1/20 0.37
BLM P54132 1/20 0.37
HIF1A Q16665 1/20 0.37
DOHH Q9BU89 1/20 0.37
P4HTM Q9NXG6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8783394 1.00 DYRK1A (0.43) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL12549545 0.83 GABRP (0.47) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL7444597 0.83 GABRP (0.47) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL2913253 0.81 DYRK1A (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL7678732 0.81 DYRK1A (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL2356474 0.81 DYRK1A (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL15140316 0.81 DYRK1A (0.43) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL31610805 0.80 MCHR1 (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL12124947 0.80 KCNA5 (0.41) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL31375650 0.80 MCHR1 (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed