Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913253 | 1.00 | DYRK1A (0.40) | DYRK1ADYRK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2356474 | 1.00 | DYRK1A (0.40) | DYRK1ADYRK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31375650 | 0.87 | MCHR1 (0.40) | DYRK1ADYRK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31610805 | 0.87 | MCHR1 (0.40) | DYRK1ADYRK2NPC1RAB9ASMN1; SMN2 | |
| Pyriproxyfen SCHEMBL25262618 | 0.85 | LTA4H (0.41) | LMNAPOLBHPGD | |
| SCHEMBL9618194 | 0.84 | LMNA (0.49) | SMN1; SMN2LMNACYP1A2POLBTSHR | |
| SCHEMBL12549545 | 0.83 | GABRP (0.47) | DYRK1ADYRK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7444597 | 0.83 | GABRP (0.47) | DYRK1ADYRK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2356476 | 0.81 | DYRK1A (0.43) | DYRK1ADYRK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15140316 | 0.81 | DYRK1A (0.43) | DYRK1ADYRK2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500416-B2 | FLUID FLOW; INSECTICIDE; MITICIDE | SYNGENTA CROP PROTECTION, INC. | 2002-12-31 | — | — | US | disclosed |
| US-20010021378-A1 | Pesticide | SYNGENTA CROP PROTECTION, INC. | 2001-09-13 | — | — | US | disclosed |
| EP-0909130-A1 | PESTICIDE | Novartis AG (CH) | 1999-04-21 | — | — | EP | disclosed |
| WO-1997042815-A1 | PESTICIDE | NOVARTIS AG (CH) | 1997-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021378-A1 | Pesticide | DDT, KISS1R, ACHE | DYRK1A 3497/4885DYRK2 3664/4885NPC1 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.