SCHEMBL2356474

SCHEMBL2356474

CC(COCC(C)Oc1ccccn1)Oc1ccccn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.40
DYRK2 Q92630 2/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
CCR1 P32246 1/20 0.37
CCR5 P51681 1/20 0.37
CCR8 P51685 1/20 0.37
METAP1 P53582 1/20 0.37
BLM P54132 1/20 0.37
HIF1A Q16665 1/20 0.37
DOHH Q9BU89 1/20 0.37
P4HTM Q9NXG6 1/20 0.37
TSHR P16473 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2913253 1.00 DYRK1A (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL7678732 1.00 DYRK1A (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL31375650 0.87 MCHR1 (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL31610805 0.87 MCHR1 (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
Pyriproxyfen SCHEMBL25262618 0.85 LTA4H (0.41) LMNAPOLBHPGD
SCHEMBL9618194 0.84 LMNA (0.49) SMN1; SMN2LMNACYP1A2POLBTSHR
SCHEMBL12549545 0.83 GABRP (0.47) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL7444597 0.83 GABRP (0.47) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL2356476 0.81 DYRK1A (0.43) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL15140316 0.81 DYRK1A (0.43) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US claimed
EP-0765120-A1 SYNERGISTIC COMPOSITION Novartis AG (CH) 1997-04-02 EP claimed
EP-0736252-A2 Synergistic compositions with diafenthiuron CIBA-GEIGY AG (CH) 1996-10-09 EP claimed
WO-1995033380-A1 SYNERGISTIC COMPOSITION CIBA-GEIGY AG (CH) 1995-12-14 WO claimed
CN-117941692-A Insecticidal composition containing pyriproxyfen and chlorfenapyr flubendiamide and application thereof 广西思钺生物科技有限责任公司 2024-04-30 CN disclosed
CN-117918363-A Insecticidal composition containing pyriproxyfen and cyflufenapyr and application thereof 黑龙江优创农业科技有限公司 2024-04-26 CN disclosed
EP-3797137-B1 ALL TEMPERATURE WATER BORNE SEALANT RED DEVIL INC (US) 2023-12-06 EP disclosed
CN-116242923-A Method for detecting pyriproxyfen, non-prednisone and metabolites thereof and application 天津渤海农牧产业联合研究院有限公司 2023-06-09 CN disclosed
CN-115444002-A Pyriproxyfen insecticide and preparation method thereof 春华秋实科技集团有限公司 2022-12-09 CN disclosed
CN-115281198-A Insecticidal composition for preventing and treating oriental-melon liriomyza sativae and prevention and treatment method 陕西美邦药业集团股份有限公司 2022-11-04 CN disclosed
CN-113854305-A Insecticidal composition containing pyriproxyfen and dinotefuran 华植河北生物科技有限公司 2021-12-31 CN disclosed
WO-1997040692-A1 PESTICIDAL COMPOSITIONS NOVARTIS AG (CH) 1997-11-06 WO disclosed
EP-0765120-A1 SYNERGISTIC COMPOSITION Novartis AG (CH) 1997-04-02 EP disclosed
CN-1140016-A Pesticidal composition CIBA GEIGY AG (CH) 1997-01-15 CN disclosed
EP-0736252-A2 Synergistic compositions with diafenthiuron CIBA-GEIGY AG (CH) 1996-10-09 EP disclosed
WO-1995033380-A1 SYNERGISTIC COMPOSITION CIBA-GEIGY AG (CH) 1995-12-14 WO disclosed
US-5190745-A 2,4-Dioxo-1-/2-Propynyl/imidazolidin-3-ylmethyl Chrysanthemate Ester, Kerosene, Propellant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-02 US disclosed
EP-0368285-A2 Improved pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests GAP43, GRN, DDT DYRK1A 1793/4885DYRK2 1745/4885NPC1 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.