SCHEMBL2913253

SCHEMBL2913253

C[C@H](COC[C@@H](C)Oc1ccccn1)Oc1ccccn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.40
DYRK2 Q92630 2/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
CCR1 P32246 1/20 0.37
CCR5 P51681 1/20 0.37
CCR8 P51685 1/20 0.37
METAP1 P53582 1/20 0.37
BLM P54132 1/20 0.37
HIF1A Q16665 1/20 0.37
DOHH Q9BU89 1/20 0.37
P4HTM Q9NXG6 1/20 0.37
TSHR P16473 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2356474 1.00 DYRK1A (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL7678732 1.00 DYRK1A (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL31375650 0.87 MCHR1 (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL31610805 0.87 MCHR1 (0.40) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
Pyriproxyfen SCHEMBL25262618 0.85 LTA4H (0.41) LMNAPOLBHPGD
SCHEMBL9618194 0.84 LMNA (0.49) SMN1; SMN2LMNACYP1A2POLBTSHR
SCHEMBL12549545 0.83 GABRP (0.47) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL7444597 0.83 GABRP (0.47) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL2356476 0.81 DYRK1A (0.43) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2
SCHEMBL15140316 0.81 DYRK1A (0.43) DYRK1ADYRK2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP claimed
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US claimed
EP-3797137-B1 ALL TEMPERATURE WATER BORNE SEALANT RED DEVIL INC (US) 2023-12-06 EP disclosed
US-11124633-B2 All temperature water borne sealant RED DEVIL, INC. (US) 2021-09-21 US disclosed
EP-3797137-A1 ALL TEMPERATURE WATER BORNE SEALANT Red Devil Inc. (US) 2021-03-31 EP disclosed
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP disclosed
US-9464456-B2 System for protecting stored goods BASF SE (DE) 2016-10-11 US disclosed
US-9375001-B1 Granular fly bait WELLMARK INTERNATIONAL (US) 2016-06-28 US disclosed
EP-2723156-B1 SYSTEM FOR PROTECTING STORED GOODS BASF SE (DE) 2015-06-24 EP disclosed
US-20140190075-A1 Method and Device for Protecting Crop Plants BASF SE (DE) 2014-07-10 US disclosed
US-20140190538-A1 System for Protecting Stored Goods BASF SE (DE) 2014-07-10 US disclosed
US-20050033081-A1 Aminoacetonitrile derivatives and their use for controlling parasites NOVARTIS AG (CH) 2005-02-10 US disclosed
WO-2003080577-A2 AMIDOACETONITRILE COMPOUNDS NOVARTIS AG (CH) 2003-10-02 WO disclosed
JP-2003146811-A CONTROLLING COMPOSITION FOR BARNACLES FUMAKILLA LTD 2003-05-21 JP disclosed
EP-0967875-B1 SYNERGISTIC JUVENOID/CHITIN SYNTHESIS INHIBITOR TERMITICIDE COMPOSITIONS DOW AGROSCIENCES LLC (US) 2002-01-23 EP disclosed
US-6093415-A CONTROLLING TERMITES COMPRISING A JUVENILE HORMONE MIMIC DOW AGROSCIENCES LLC (US) 2000-07-25 US disclosed
EP-0977483-A1 PESTICIDAL COMPOSITION Novartis AG (CH) 2000-02-09 EP disclosed
WO-1998047368-A1 PESTICIDAL COMPOSITION NOVARTIS AG (CH) 1998-10-29 WO disclosed
US-5190745-A 2,4-Dioxo-1-/2-Propynyl/imidazolidin-3-ylmethyl Chrysanthemate Ester, Kerosene, Propellant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-02 US disclosed
EP-0368285-A2 Improved pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050033081-A1 Aminoacetonitrile derivatives and their use for controlling parasites NAT1, ALDH7A1, AAAS DYRK1A 1898/4885DYRK2 1827/4885NPC1 4009/4885
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests GAP43, GRN, DDT DYRK1A 1793/4885DYRK2 1745/4885NPC1 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.