Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566392 | 0.90 | PTK2 (0.32) | — | |
| SCHEMBL23566369 | 0.77 | LCK (0.38) | BUB1 | |
| SCHEMBL23566404 | 0.77 | FOLH1 (0.34) | — | |
| SCHEMBL23566351 | 0.76 | HSP90AA1 (0.35) | MAOAMAOB | |
| SCHEMBL23566399 | 0.73 | AURKA (0.36) | — | |
| SCHEMBL23566396 | 0.73 | ACHE (0.36) | — | |
| SCHEMBL8295015 | 0.73 | MAOA (0.38) | CYP2A6MAOAMAOBNOS3NOS1 | |
| SCHEMBL27089176 | 0.73 | PSMB1 (0.50) | MAOAMAOBBUB1 | |
| SCHEMBL23566371 | 0.72 | HCRTR1 (0.38) | MAOAMAOB | |
| SCHEMBL19152890 | 0.71 | BRD4 (0.37) | CYP2A6MAOAMAOBNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | claimed |
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |