Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664591 | 0.85 | FAAH (0.50) | FAAHCYP1A2GLANAAAMEN1 | |
| SCHEMBL10064157 | 0.82 | FAAH (0.86) | FAAHEPHX2GAAMEN1KMT2A | |
| SCHEMBL13268369 | 0.82 | FAAH (0.86) | FAAHEPHX2GAAMEN1KMT2A | |
| SCHEMBL5650328 | 0.81 | ITGB3 (0.47) | FAAHGLA | |
| SCHEMBL9618659 | 0.79 | FAAH (0.81) | FAAHEPHX2GAAMEN1KMT2A | |
| SCHEMBL22591880 | 0.78 | CYP1A2 (0.40) | FAAHTRPV1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6392805 | 0.77 | HPGD (0.56) | CYP1A2CYP2C9CYP2C19GAAGLA | |
| SCHEMBL22260401 | 0.76 | CASP2 (0.56) | FAAHEPHX2NAAA | |
| SCHEMBL25834507 | 0.76 | CASP2 (0.56) | FAAHEPHX2NAAA | |
| N-Ethylpalmitamide SCHEMBL4148137 | 0.76 | FAAH (1.00) | FAAHEPHX2NAAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127305-A1 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER STEM CELLS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2021-06-24 | — | — | WO | disclosed |