Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23568846 | 0.79 | PTGS1 (0.39) | CXCR1CXCR2PTGS1MAPK14KAT2B | |
| SCHEMBL9627350 | 0.74 | PTGS1 (0.40) | CXCR1CXCR2PTGS1KAT2BKMT2A | |
| SCHEMBL23569352 | 0.69 | SMN1; SMN2 (0.39) | KAT2BKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10594957 | 0.68 | PTGS1 (0.40) | CXCR1CXCR2PTGS1KMT2ATSHR | |
| SCHEMBL11732818 | 0.67 | MAPT (0.45) | KMT2ATSHRALDH1A1LMNAMAPT | |
| SCHEMBL970491 | 0.67 | PTGS1 (0.39) | CXCR1CXCR2PTGS1KMT2ATSHR | |
| SCHEMBL22303067 | 0.66 | MAPT (0.39) | CXCR1CXCR2PTGS1KAT2BALDH1A1 | |
| SCHEMBL16724105 | 0.66 | SMN1; SMN2 (0.41) | CXCR1CXCR2PTGS1KMT2ATSHR | |
| SCHEMBL16200678 | 0.66 | PKM (0.39) | CXCR1CXCR2PTGS1KMT2ATSHR | |
| SCHEMBL12471098 | 0.66 | RAB9A (0.57) | CXCR1CXCR2MAPK14KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123237-A1 | 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE | Oxford Drug Design Limited (GB) | 2021-06-24 | — | — | WO | disclosed |