Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23568847 | 0.72 | KMT2A (0.42) | SMN1; SMN2MITFS1PR4LMNAHPGD | |
| SCHEMBL23569353 | 0.69 | CXCR1 (0.40) | LMNAHTTMAPTCA12CA2 | |
| SCHEMBL23406137 | 0.66 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHPGDHTTNPSR1 | |
| SCHEMBL28101227 | 0.65 | MAPT (0.59) | SMN1; SMN2MITFS1PR4LMNAHPGD | |
| SCHEMBL7874157 | 0.64 | KMT2A (0.71) | MAPK1LMNAALDH1A1KMT2ACYP3A4 | |
| SCHEMBL11922841 | 0.64 | TSHR (0.55) | LMNAHTTMAPTCA12CA2 | |
| SCHEMBL23406145 | 0.63 | HTT (0.42) | SMN1; SMN2MITFS1PR4LMNAHPGD | |
| SCHEMBL9330309 | 0.63 | VCAM1 (0.49) | SMN1; SMN2MITFS1PR4LMNAHPGD | |
| SCHEMBL7870908 | 0.63 | ALDH1A1 (0.62) | LMNAHTTNPSR1MAPTALDH1A1 | |
| SCHEMBL7874047 | 0.63 | KMT2A (0.53) | LMNAHTTNPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123237-A1 | 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE | Oxford Drug Design Limited (GB) | 2021-06-24 | — | — | WO | disclosed |