Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 16/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 16/20 | 0.42 |
| ▸ | GABRD | O14764 | 15/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 15/20 | 0.42 |
| ▸ | GABRP | O00591 | 13/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 13/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 13/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 13/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 13/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 13/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 13/20 | 0.42 |
| ▸ | GABRE | P78334 | 13/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 13/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 13/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 13/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 13/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833944 | 0.81 | GABRD (0.42) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL12178067 | 0.81 | SHBG (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL15164711 | 0.81 | SHBG (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL16189884 | 0.81 | SHBG (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL12178022 | 0.81 | SHBG (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL4834980 | 0.81 | GABRD (0.42) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL28139742 | 0.78 | GRIN1 (0.41) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL1173075 | 0.78 | GRIN1 (0.41) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL27374318 | 0.77 | GABRA1 (0.42) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL7028261 | 0.77 | GABRA1 (0.42) | GABRA1GABRB2GABRDGABRA4GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512107-B2 | Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-11-29 | — | — | US | disclosed |
| US-20210188898-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | TRUSTEES OF DARTMOUTH COLLEGE | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188898-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | C9, NDC1, RTCB | GABRA1 1489/4885GABRB2 1300/4885GABRD 482/4885 |
| US-11512107-B2 | Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation | C9, NDC1, RTCB | GABRA1 1489/4885GABRB2 1300/4885GABRD 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.