Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 11/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 11/20 | 0.42 |
| ▸ | GABRP | O00591 | 10/20 | 0.42 |
| ▸ | GABRD | O14764 | 10/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.42 |
| ▸ | GABRE | P78334 | 10/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025455 | 0.78 | SHBG (0.44) | CYP17A1SHBG | |
| SCHEMBL12178067 | 0.77 | SHBG (0.62) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL4834980 | 0.77 | GABRD (0.42) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL4833944 | 0.77 | GABRD (0.42) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL16189884 | 0.77 | SHBG (0.62) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL23569462 | 0.77 | GABRA1 (0.42) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL15164711 | 0.77 | SHBG (0.62) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL12178022 | 0.77 | SHBG (0.62) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL22033067 | 0.75 | GABRA1 (0.71) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL7315413 | 0.75 | GABRA1 (0.71) | GABRA1GABRB2GABRPGABRDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994713-B1 | USE OF A 7alpha-METHYL-17alpha-ETHYNYL-ESTRANE DERIVATIVE FOR THE TREATMENT OF ATHEROSCLEROSIS | AKZO NOBEL NV (NL) | 2003-11-05 | — | — | EP | claimed |
| EP-0169515-B1 | 17-HALOVINYL ESTRANE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN MEDICINES | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | claimed |