Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546113 | 1.00 | LMNA (0.41) | LMNAMAPTNPSR1HTTCYP3A4 | |
| SCHEMBL6546116 | 1.00 | LMNA (0.41) | LMNAMAPTNPSR1HTTCYP3A4 | |
| SCHEMBL16857588 | 0.94 | GABRA1 (0.39) | LMNAMAPTNPSR1HTTCYP3A4 | |
| SCHEMBL6547045 | 0.86 | LMNA (0.40) | LMNAMAPTNPSR1HTTCYP3A4 | |
| SCHEMBL6547041 | 0.86 | BRD4 (0.36) | LMNAMAPTNPSR1HTTCYP3A4 | |
| SCHEMBL6546371 | 0.86 | BRD4 (0.36) | LMNAMAPTNPSR1HTTCYP3A4 | |
| SCHEMBL10340181 | 0.80 | TBXAS1 (0.38) | HTTCYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL10340182 | 0.80 | TBXAS1 (0.38) | HTTCYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL5485410 | 0.78 | AKR1C3 (0.55) | HTTCYP2C9 | |
| SCHEMBL16474260 | 0.77 | GABRA1 (0.40) | LMNAMAPTNPSR1HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021125279-A1 | CHEMICALLY CROSSLINKED ALGINATE GEL FIBER | 持田製薬株式会社 | 2021-06-24 | — | — | WO | disclosed |