SCHEMBL8979358

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1551997	0.84	TPMT (0.50)	TPMTHCAR1TTRNPC1RAB9A
	SCHEMBL1097743	0.84	TPMT (0.50)	TPMTHCAR1TTRRXRARXRB
	SCHEMBL27709068	0.84	TPMT (0.59)	TPMTHCAR1HCAR2TTRMRGPRX4
	SCHEMBL6954785	0.82	TPMT (0.61)	TPMTHCAR1HCAR2TTRMRGPRX4
	SCHEMBL3488223	0.82	ADRA1D (0.50)	TPMTHCAR1RAB9ASMN1; SMN2TSHR
	SCHEMBL69625	0.79	TPMT (0.89)	TPMTHCAR1HCAR2TTRRXRA
	SCHEMBL28214359	0.79	TPMT (1.00)	TPMTHCAR1HCAR2TTRRXRA
	SCHEMBL23699	0.79	TPMT (1.00)	TPMTHCAR1HCAR2TTRRXRA
	SCHEMBL11771738	0.79	TPMT (0.57)	TPMTHCAR1HCAR2TTRMRGPRX4
	SCHEMBL28186397	0.79	TPMT (0.57)	TPMTHCAR1HCAR2TTRMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.