Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 6/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357713 | 0.84 | HCRTR1 (0.42) | HCRTR1HCRTR2SORT1 | |
| SCHEMBL2357650 | 0.81 | CSF1R (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL2357216 | 0.80 | HCRTR1 (0.40) | HCRTR1HCRTR2SORT1P2RX1 | |
| SCHEMBL2358322 | 0.79 | SORT1 (0.53) | HCRTR1HCRTR2SORT1 | |
| SCHEMBL2359300 | 0.76 | BRAF (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2359008 | 0.75 | HCRTR1 (0.41) | HCRTR1HCRTR2SORT1 | |
| SCHEMBL2358231 | 0.75 | CHRM1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL2355869 | 0.74 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2356052 | 0.73 | KDM4E (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2363797 | 0.72 | HCRTR1 (0.43) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350052-A2 | ANTIPROLIFERATIVE COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2011-08-03 | — | — | EP | claimed |
| WO-2010034838-A2 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |