Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28184365 | 0.86 | CTSK (0.47) | CTSKCA1CA2ALDH1A1FAAH | |
| SCHEMBL2897891 | 0.85 | CA1 (0.52) | CA1ALDH1A1FAAHLMNA | |
| SCHEMBL15821165 | 0.85 | CTSK (0.46) | CTSKCA1CA2ALDH1A1FAAH | |
| SCHEMBL26050331 | 0.81 | CA2 (0.48) | CTSKCA1CA2ALDH1A1PRKCA | |
| SCHEMBL28853048 | 0.81 | FAAH (0.44) | CTSKCA1ALDH1A1FAAHLMNA | |
| SCHEMBL24786197 | 0.80 | DPP7 (0.43) | CTSKCA1CA2FAAHPRKCA | |
| SCHEMBL10332027 | 0.80 | MAPT (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL20398330 | 0.80 | GPR84 (0.49) | MEN1KMT2AFAAHLMNATSHR | |
| SCHEMBL20398338 | 0.80 | GPR84 (0.49) | MEN1KMT2AFAAHLMNATSHR | |
| SCHEMBL2339946 | 0.79 | CTSK (0.51) | CTSKCA1CA2PRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381469-B1 | ANTI-ERBB2 ANTIBODY-DRUG CONJUGATE AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) | 2021-06-30 | — | — | EP | disclosed |