SCHEMBL23588141

SCHEMBL23588141

C=C(Cc1nc(-c2ccc(OCCCC)c(F)c2)no1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GSTP1 P09211 6/20 0.43
▸ MAPK1 P28482 1/20 0.42
▸ FFAR1 O14842 1/20 0.42
▸ MAPT P10636 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ BCHE P06276 1/20 0.41
▸ ACHE P22303 1/20 0.41
▸ MITF O75030 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ NCOA3 Q9Y6Q9 1/20 0.41
▸ ACACB O00763 1/20 0.40
▸ ACACA Q13085 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29844146 0.88 TDP1 (0.50) GSTP1FFAR1MAPTLMNAL3MBTL1
SCHEMBL23588172 0.88 TDP1 (0.50) GSTP1FFAR1MAPTLMNAL3MBTL1
SCHEMBL29973428 0.88 GSTP1 (0.40) GSTP1MAPK1FFAR1MAPTTP53
SCHEMBL23578220 0.88 GSTP1 (0.40) GSTP1MAPK1FFAR1MAPTTP53
SCHEMBL23588193 0.87 SPHK2 (0.49) —
SCHEMBL29844119 0.87 SPHK2 (0.49) —
SCHEMBL23578421 0.87 MITF (0.41) GSTP1FFAR1LMNAMITFTP53
SCHEMBL23578433 0.84 ACACB (0.57) FFAR1MAPTLMNAL3MBTL1MITF
SCHEMBL23578296 0.83 S1PR1 (0.49) GSTP1MAPK1FFAR1MAPTLMNA
SCHEMBL27291369 0.82 MITF (0.43) GSTP1FFAR1MAPTLMNABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617762-B2 Carboxy derivatives with antiinflamatory properties SITRYX THERAPEUTICS LIMITED (GB) 2026-05-05 — — US disclosed
EP-4081511-B3 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2026-03-04 — — EP disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 — — US disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 — — US disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 — — US disclosed
EP-4081511-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2022-11-02 — — EP disclosed
CN-115066418-A Carboxy derivatives with anti-inflammatory properties 西特瑞治疗有限公司 2022-09-16 — — CN disclosed
WO-2021130492-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2021-07-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 GSTP1 1176/4885MAPK1 3947/4885FFAR1 1711/4885
US-12617762-B2 Carboxy derivatives with antiinflamatory properties CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 GSTP1 320/4885MAPK1 3978/4885FFAR1 1156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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