Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291368 | 0.87 | ACACB (0.39) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL23578433 | 0.87 | ACACB (0.57) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL23588141 | 0.82 | GSTP1 (0.43) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL23588172 | 0.82 | TDP1 (0.50) | MAPTHTTLMNAFFAR1GSTP1 | |
| SCHEMBL29844146 | 0.82 | TDP1 (0.50) | MAPTHTTLMNAFFAR1GSTP1 | |
| SCHEMBL23578438 | 0.82 | ACACB (0.64) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL27291464 | 0.81 | NPC1 (0.41) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL29844119 | 0.80 | SPHK2 (0.49) | — | |
| SCHEMBL23588193 | 0.80 | SPHK2 (0.49) | — | |
| SCHEMBL30689438 | 0.79 | LMNA (0.51) | MITFTP53NCOA3MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127030-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |